Double Marker Test – Early Screening for Fetal Chromosomal Abnormalities
The Double Marker Test is a crucial prenatal screening performed during the first trimester of pregnancy, usually between the 9th and 13th weeks. This blood test measures levels of Free Beta-hCG and PAPP-A (Pregnancy-Associated Plasma Protein A) to assess the risk of chromosomal abnormalities such as Down syndrome (Trisomy 21) and Edwards syndrome (Trisomy 18) in the developing fetus. Often combined with a Nuchal Translucency (NT) scan, the Double Marker Test provides a more accurate risk estimate for expecting parents. Although it is not a diagnostic test, it plays an important role in identifying pregnancies that may need further evaluation through advanced methods like NIPT or amniocentesis. Being non-invasive and safe, the Double Marker Test offers peace of mind and valuable insight into the baby’s genetic health, supporting better-informed decisions during early pregnancy care.
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13-Jun-2025 10:56 am
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